Neurological Differential Diagnosis: A Prioritized Approach by Roongroj Bhidayasiri

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By Roongroj Bhidayasiri

Neurology is basically characterised by means of numerous ailments which appear very related and are for that reason tough to differentiate among. ability at differential prognosis is for that reason totally paramount.

Neurological Differential Diagnosis is a streamlined instruction manual of prioritized differential analysis, for use either in scientific perform and for examination review.

By proposing differential analysis so as of frequency and value, this booklet offers a realistic instruction manual for clinicians in education, in addition to a possible source for speedy board overview. when the booklet covers crucial syndromes and disorder entities, readers are talked about different texts for extra exhaustive differentials. through restricting differentials during this method - to the main most likely and such a lot critical diagnoses - the reader can extra simply remember appropriate disorder methods whilst confronted with a specific scientific state of affairs, even if or not it's a sufferer within the emergency room or a tough query at the board examination.

The e-book in particular objectives neurology citizens and fellows, with overlap to neurosurgery and psychiatry. inner drugs physicians with an curiosity in neurological difficulties and clinical scholars searching for an part in medical neuroscience may additionally reap the benefits of this text.

The content material is basically mid-level fabric, in a pedagogic format.

In order to arrange the scholars' proposal tactics concise tables and line drawing templates are incorporated. The publication is equipped into extensive chapters through kind of affliction and a few overlap happens among specific chapters.

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In general, ascending axons synapse within the spinal cord before decussating. G. Clinical Neuroanatomy, 25th edn, 2003, New York, Lange Medical Books/McGraw-Hill. Descending fiber systems in the spinal cord • • Examination of a cross-section of the spinal cord reveals major descending tracts, including corticospinal tract, vestibulospinal tract, rubrospinal tract, reticulospinal tract, descending autonomic tract, tectospinal tract, and medial longitudinal fasiculus. The corticospinal fibers originate in the contralateral cerebral cortex, and 90% of its fibers cross in the decussation of the medullary pyramids, with the remaining 10% traveling ipsilaterally as anterior corticospinal tract.

However, spinal cord metastases are rare and are generally seen at the terminal stage of the disease process. The most common tumors to metastasize to the brain include lung, breast, melanoma, renal cell carcinomas, and choriocarcinoma. If one resorts to immunohistochemistry to distinguish a metastatic lesion from glioma, extra care needs to be taken not to confuse cross reactivity patterns of staining with certain markers. g. 2 Neuroanatomy and Neuropathology 49 Tumors: gliosis vs. glioma • • • One of the most challenging differential diagnostic problems in surgical neuropathology is to distinguish between gliosis or reactive astrocytosis and a low-grade glial tumor.

Diffuse lesions Open biopsy • More tissue can be acquired. • Usually performed under general anesthesia. • Dural and arachnoid biopsies can be obtained. • A specimen is usually of 1 cm in size of cortex and underlying white matter. • Right frontal lobe is commonly chosen for biopsy unless a focal area of more intense involvement is identified. Arteriovenous malformation versus cavernous malformation • • • • Four types of vascular malformations are recognized: ◆ Arteriovenous malformation (AVM) ◆ Cavernous malformation (CM) ◆ Venous malformation (VM) ◆ Capillary telangiectasia (CaT) AVMs and CMs are commonly seen surgically, while VMs and CaTs are often seen incidentally at autopsy.

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