Molecular Dissection of Complex Traits by Andrew H. Paterson

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By Andrew H. Paterson

Some time past 10 years, modern geneticists utilizing new molecular instruments were capable of unravel advanced characteristics into person genetic elements and describe each one such part intimately. Molecular Dissection of advanced features summarizes the cutting-edge in molecular research of advanced characteristics.

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And Ganal, M. , Abundance, variability and chromosomal location of microsatellites in wheat, Mol. Gen. , 246, 327, 1995. 116. , and Olivieri, A. , Genetic mapping and variability of seven soybean simple sequence repeat loci, Genome, 37, 763, 1994. 117. Saghai-Maroof, M. , Biyashev, R. , Yang, G. , and Allard, R. , Extraordinarily polymorphic microsatellite DNA in barley: species diversity, chromosomal locations and population dynamics, Proc. Nat. Acad. Sci. , 91, 5466, 1994. 118. , Shiu, O. , and Mitchelson, K.

8 SUMMARY The past decade has proven to be a golden era for eukaryotic genetics. Technical advances have provided geneticists with the ability to infer the locations of many important genes, and to manipulate genes and genotypes with a level of precision previously impossible. As maps and markers progress from laboratory curiosities to practically important tools, the technologies utilized for genotype analysis will become progressively more robust and reliable. Currently, in addition to RFLP analysis, the most promising new methods for map construction appears to be a combination © 1998 by CRC Press LLC Molecular Tools for the Study of Complex Traits 23 of AFLP and multiplexed microsatellite analysis.

Orlin, J. , Birren, B. , Hawkins, T. , Page, D. , and Lander, E. , An STS-based map of the human genome, Science, 270, 1945, 1995. 131. , and Khush, G. , Classification of rice germplasm. I. Analysis using ALP and PCR-based RFLP, Theor. Appl. , 91, 218, 1995. 132. Chee, P. , and Talbert, L. , Molecular analysis of evolutionary patterns in U genome wild wheats, Genome, 38, 290, 1995. 133. , Hayes, P. , and Blake, T. , Sequence-tagged-site facilitated PCR for barley genome mapping, Theor. Appl. , 84, 1002, 1992.

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