By Christopher K. Mathews (auth.), Kenneth W. Adolph (eds.)
Chromosomes have constitution, made up our minds via the interactions of proteins with DNA, and chromosomes have capabilities, specifically, replication of DNA and transcription of messenger RNA. Chromosome constitution and serve as should not separate subject matters, when you consider that chromosome association professional foundly impacts the task of the genome in replication and transcrip tion. this is often in particular transparent for larger cells, together with human cells, within which chromatin fibers are created by way of the binding of histone proteins to the DNA, and folding of the fibers produces mitotic chromosomes and interphase nuclei. The complex association of DNA in greater cells is now famous as being heavily concerned with genome task. Many basic effects have originated from stories of bacterial and viral structures, that have been platforms of selection due to their much less complicated existence cycles. The strategies of replication and transcription express adjustments among the better and less complicated platforms (e. g. , various enzymes and protein elements are involved). however the parallels are as outstanding because the variations intimately. Even for micro organism and viruses, an entire realizing of those tactics would require integrating the result of molecular biology with these of structural biology and mobilephone biology. 3 vital matters are lined during this quantity: DNA replication and recombination, gene transcription, and chromosome association. The sections facing replication and transcription research fresh effects acquired via employing the ideas of molecular biology and biochemistry. Eukaryotic, prokaryotic, and viral platforms are discussed.
Read or Download Molecular Biology of Chromosome Function PDF
Similar biology books
“Because we get pleasure from interacting with biology lower than- grads and imagine that they need to have biology textbooks which are basically written, make the subject material proper to the reader, and support them enjoy not just how a lot we already learn about biology—cell biology, in our case—but additionally how even more continues to be investi- gated and came across.
Long non-coding RNAs (lnc)RNAs have emerged as a brand new paradigm in epigenetic law of the genome. millions of lncRNAs were pointed out and saw in a variety of organisms. in contrast to mRNA, lncRNA don't have any protein-coding skill. So, whereas their functionality isn't really totally transparent, they could function key organizers of protein complexes that let for better order regulatory occasions.
The variety of antigen-binding buildings of antibody molecules is so sizeable that each attainable antigen will be certain through an antibody molecule in the immune process. this is often actual even for the antigen binding websites of antibodies known as idiotypes, that are sure via complementary bind ing websites of alternative antibodies known as anti-idiotypes.
- In Situ Hybridization Protocols (Methods in Molecular Biology Vol 33)
- Kimmeridgiense-Tithonico inferior en el Sector central de las Cordilleras Béticas (Zona Subbética)
- Embryonic Stem Cell Protocols 2nd Edition, Volume 1: Isolation And Characterization (Methods in Molecular Biology Vol 329)
- Transactions on Computational Systems Biology X
Additional resources for Molecular Biology of Chromosome Function
Acad. Sci. USA 83, 986-990. 47. , and Reichard, P. (1987) Mol. Cell. BioI. 7, 4218-4224. 48. , and Reichard, P. (1986) J. BioI. Chern. 261, 1603716042. 49. W. W. (1981) Annu. Rev. Biochem. 50, 845-877. 50. J. (1988) J. BioI. Chern. 263, 1494-1499. 51. c. (1987) J. BioI. Chern. 262, 5288-5292. 52. Meuth, M. (1984) Mutat. Res. 126, 107-112. K. Mathews 53. , ed. (1985) Genetic Consequences of Nucleotide Pool Imbalance. Plenum Press, New York. 54. R. (1979) Proc. Natl. Acad. Sci. USA 76, 4946-4950.
1987) In DNA Replication and Recombination. , eds. Alan R. Liss, New York. 7. c. (1983) Cell 33, 315-318. 8. , and White, J. (1987) In DNA Replication and Recombination. , eds. Alan R. Liss, New York. 9. S. (1984) J. BioI. Chern. 259, 12117-12122. 10. c. (1975) J. BioI. Chern. 250,5508-5514. 11. , and Kornberg, A. (1968) J. BioI. Chern. 243, 627-638. 12. C. (1979) J. BioI. Chern. 254, 11591-11597. 13. , and Modrich, P. (1979) J. BioI. Chern. 254, 11605-11614. 14. c. (1987) J. BioI. Chern. 262, 16212-16223.
And Isono, K. (1987) Cell 50, 495-508. 68. H. (1979) Mol. Gen. Genet. 177, 103-112. 69. , and Drlica, K. (1984) Cell 36, 1081-1088. 70. R. (1979) J. Bacteriol. 140, 424-435. 71. , and Snyder, M. (1978) J. Mol. BioI. 120, 145-154. 72. R. (1987) J. Mol. BioI. 194, 205-218. 73. R. (1977) Proc. Natl. Acad. Sci. USA 74, 4767-4771. 74. , and Gellert, M. (1978) Proc. Natl. Acad. Sci. USA 75, 5960-5963. 75. R. (1979) Proc. Natl. Acad. Sci. USA 75, 1773-1777. 76. , and Nash, H. (1976) Proc. Natl. Acad.