Mathematical foundations of programming by F. S. Beckman

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By F. S. Beckman

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J Cell Sci 101: 183-189 Orita M, Sekiya T, Hayashi K (1990) DNA sequence polymorph isms in ALU repeats. Genomics: 8: 271-278 Orita M, Suzuki Y, Sekiya T, Hayashi K (1989) Rapid and sensitive detection of point mutations and DNA polymorph isms using the polymerase chain reaction. Genomics 5: 874-879· Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory handbook. 104 Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Nat! Acad Sci USA 74: 5463-5467 Scholz RB, Milde-Langosch K, Jung R, Schlechte H, Kabisch H, Wagener C, LoningT (1993) Rapid screening to Tp53 mutations by temperature-gradient gel electrophoresis: a comparison with SSCP analysis.

The potential outcomes of TOS can be studied and documented, and follow up will assist researchers in the United States who are studying the evolution of eosinophilia-myalgia syndrome (EMS) (Philen 1993). The clinical resemblance of TOS and EMS is remarkable, 51 and investigators have proposed the hypothesis that they may have related etiologies. Features of TOS and EMS are similar to those of several immunologic diseases. Studies of drug induced lupus (Jiang 1994) have suggested that environmental exposures may lead to connective tissue diseases and that these diseases may be related etiologically.

This study showed a dose-response relationship between the amount of an aniline-derived fatty acid, oleyl anilide, and the risk of becoming ill (Kilbourne 1988). This study, carried out in two Madrid locations, was replicated two years later by a study that included all the areas affected by the epidemic (Posada 1994). These two studies support both the conclusion that consumption of contaminated oil was important and that a definite dose-response relationship existed between the chemical compounds found in the oils and the risk of developing illness.

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