Liposomes Part E by Duzgunes N. (ed.), Abelson J. N. (ed.), Kaplan N. O. (ed.)

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By Duzgunes N. (ed.), Abelson J. N. (ed.), Kaplan N. O. (ed.)

Liposomes are mobile buildings made of lipid molecules. very important as a mobile version within the learn of simple biology, liposomes also are utilized in scientific purposes corresponding to drug supply and virus experiences. Liposomes half E is a continuation of prior MIE Liposome volumes A, B, C and D.* probably the most hugely revered guides within the box of biochemistry due to the fact 1955* often consulted, and praised by way of researchers and reviewers alike* really an important booklet for somebody in any box of the existence sciencesAnnotationLiposomes are mobile buildings made from lipid molecules. vital as a mobile version within the research of easy biology, liposomes also are utilized in medical purposes reminiscent of drug supply and virus reports. Liposomes half E is a continuation of prior MIE Liposome volumes A, B, C and D. essentially the most hugely revered guides within the box of biochemistry due to the fact 1955

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And Bally, M. B. (1993). Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia. Cancer Chemother. Pharmacol. 33, 17–24. Mayer, L. , Tai, L. , Ko, D. , Ginsberg, R. , Cullis, P. , and Bally, M. B. (1989). Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice. Cancer Res. 49, 5922–5930. , and Colombo, M. P. (1991). s c-myb. Cancer Res. 51, 2897–2901.

M. (2001). Liposomal encapsulated anthracyclines: New therapeutic horizons. Curr. Oncol. Rep. 3, 156–162. Muindi, J. , Sinha, B. , and Myers, C. E. (1984). Hydroxyl radical production and DNA damage induced by anthracycline-iron complex. FEBS Lett. 172, 226–230. Northfelt, D. , Dezube, B. , Thommes, J. , Miller, B. , Fischl, M. , Kaplan, L. , Du, M. , Mamelok, R. , and Henry, D. H. (1998). Pegylatedliposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi’s sarcoma: Results of a randomized phase III clinical trial.

Drug uptake is monitored as described above. Encapsulation of Genetic Drugs within LUVs: Long-Circulating Vectors for the Systemic Delivery of Genes and Antisense Oligonucleotides The development of genetic drugs, such as antisense oligonucleotides or plasmid DNA carrying a therapeutic gene, holds great promise in the treatment of acquired diseases such as cancer and inflammation. Much current effort is directed at development of gene delivery vehicles capable of accessing distal disease sites following systemic (intravenous) administration.

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