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Extra info for Immunological Approaches to Embryonic Development and Differentiation Part II
The results indicate that both “embryonic-type” and “adult-type” stem cells are Thy-1 positive. This is of interest because these two stem cell populations differ considerably with respect to their physical characteristics and proliferative capacities. “Embryonic-type” stem cells are large low-density cells with extensive proliferative capacities, whereas “adult-type” stem cells are smaller, higher density cells with more limited proliferative capacities (Metcalf and Moore, 1971). The presence of Thy-1 antigens on both of these populations is consistent with other evidence which suggests that they bear a precursor-product relationship.
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