By Dongqing Li
A lab-on-a-chip machine is a microscale laboratory on a credit-card sized glass or plastic chip with a community of microchannels, electrodes, sensors and digital circuits.These labs on a chip can reproduction the really expert services as played via their room-sized opposite numbers, equivalent to scientific diagnoses, PCR and electrophoretic separation. some great benefits of those labs on a chip comprise major aid within the quantities of samples and reagents, very brief response and research time, excessive throughput and portability.Generally, a lab-on-a-chip machine needs to practice a few microfluidic features: pumping, blending, thermal cycling/incubating, dishing out, and keeping apart. unique manipulation of those microfluidic approaches is vital to the operation and function of labs on a chip.The target of this publication is to supply a basic knowing of the interfacial electrokinetic phenomena in numerous key microfluidic strategies, and to teach how those phenomena should be utilised to manage the microfluidic procedures. For this objective, this ebook emphasises the theoretical modelling and the numerical simulation of those electrokinetic phenomena in microfluidics. even if, experimental experiences of the electrokinetic microfluidic methods also are highlighted in adequate aspect. * the 1st publication which systematically stories electrokinetic microfluidics procedures for lab-on-a chip purposes* Covers modelling and numerical simulation of the electrokinetic microfluidics approaches* offering info on experimental stories and info of experimental suggestions, that are crucial if you happen to are new to this box
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Additional resources for Electrokinetics in Microfluidics
Here Ps and Ac are the wetting parameter and the crosssection area of the channel, respectively. Xb is the bulk conductivity of the solution and Xs is the surface conductivity that can be determined experimentally . Substituting Eq. (39) for p e (Y,Z)into Eq. (53) and Eq. (55), the non-dimensional induced field strength can be expressed as (56) Here the nondimensional number The substitution of w(Y,Z) from Eq. (48) into Eq. , KC1) solution through a rectangular microchannel with a height of 20 urn, width of 30 urn and length of lcm.
As the ions move, they drag the surrounding liquid molecules to move with them due to the viscous effect, resulting in a bulk liquid motion. Such a liquid motion is called the electroosmotic flow. For example, by applying an electric field along a microchannel, we can electroosmotically "pump" liquids to flow through the microchannel. Electrophoresis Consider a (solid, liquid or gas) particle in a bulk liquid phase. When an electric field is applied to the bulk liquid, because the particle surface has electrostatic charge, the particle can be induced to move (relative to the stationary or moving liquid) under the applied electrical field.
A smaller EDL thickness, the effect of the EDL is less. Therefore fewer ions are carried to the downstream with the flow and hence a weaker streaming current and streaming potential are produced. (22)) by considering the EDL effects on the liquid flow. (48), the velocity field in a rectangular microchannel depends on the EDL field. Since the bulk ionic concentration and the shape of the channel's cross-section will affect the EDL field, these factors will in turn influence the velocity field.