EAGC Course Book on Colposcopy by Péter Bösze, David M. Luesley

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By Péter Bösze, David M. Luesley

In accordance with a direction run via the eu Academy of Gynecological melanoma (EAGC), EAGC path e-book on Colposcopy is an element education handbook, half atlas. Edited through Peter Bosze and David Leusley, it's a worthy source and coaching instrument. The bankruptcy authors were conscientiously selected for his or her distinctive talents of their specific box. Combining updated and finished assurance with sensible suggestions, the wonderful didactic textual content and top of the range illustrations offer an incredible synopsis for either trainees and place of work practitioners. The e-book covers every little thing a trainee colposcopist must comprehend and reports every thing expert colposcopist must keep in mind.

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Song A. The human uterus: morphogenesis and embryological basis for cancer. Thomas. Illinois, 1964. 12. Smedts F, Ramaeker FCS, Vootjs PG. The dynamics of keratin expression in malignant transformation of cervical epithelium; a review. Obstet Gynecol 1993; 82:465^174. ACKNOWLEDGEMENTS • We would like to acknowledge and thank Dr Malcolm Anderson, Department of Histopathology, Queens Medical Centre, Nottingham, UK: for granting their permission, allowing the use of Figures ΙΟα-b, Figures 13a-b. in the prepara- tion of this chapter.

I NORMAL EPITHELIUM The cervical surface is covered by a multi-layered squamous cell epithelium on the ectocervix and a single-layer columnar epithelium in the cervical canal, joining in the squamo-columnar junction (SCJ). Originally, during fetal life, the entire cervix, and part of the proximal vagina, were covered by columnar epithelium, which in turn, transformed into squamous cell epithelium after birth. The transformation zone is demarcated by the new SCJ towards the endocervical canal, whereas the ectocervical border is often not clear since mature squamous cell epithelium has completely replaced the columnar epithelium.

A single layer of columnar cells (1) can be seen above the row of "reserve cells" (2). b) Mucin-containing columnar cells (1) and residual glands (2) can be seen on the surface of the developing squamous epithelium (arrow). HISTOLOGICAL APPEARANCE The squamous metaplastic process appears to be preceded by the appearance of new cell types beneath the columnar epithelium. They are known as sub-columnar (4) or reserve cells. These cells multiply in number and eventually form the squamous epithelial layers.

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